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Diabetic Cat Care
ANESTHESIA 101
A Necessary Evil |
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To
most cat owners
- diabetic or not - it
is very frightening being told your cat needs to be anesthetized for a
procedure. Yet, the use of anesthetics is common in veterinary practices, and
provides an essential tool for surgical or other painful procedures
such as dental cleanings.
Please do NOT choose the recently popular "anesthesia free" dentals procedures
as they are terrifying for your cat.
Post Operative Anesthesia
used for
Sedation
Cats are generally given sedatives or
tranquilizers, either singly or in combination, prior to
or as a first step in the induction of
anesthesia. These drugs sedate and calm the animal
prior to
introduction of
a mask or tracheal tube required for an inhalant
anesthesia. Sedatives
allow for a smaller amount of general anesthetic
needing to be used; help to
minimize vomiting; and allow for a quicker recovery period. Sedating drugs are
generally administered by injection, intravenously for the most part, although
Ketamine can be given intramuscularly. Injectable anesthetics are also used for
relatively quick procedures, such as C-sections or spay/neutering.
Injectable anesthetic agents fall into
three main groups: Barbiturates, Dissociative Anesthetics (DAs), and
Non-barbiturate Hypnotics. Acepromazine or acetylpromazine (more commonly known
as ACP, Ace, or by the trade names Atravet or Acezine 2), the most commonly used
sedative, is used in conjunction with an analgesic such as pethidine or
buprenorphine to provide a reliable sedation.
Propofol (a non-barbiturate hypnotic), is the "injectable of choice" for certain veterinary procedures, as it is quick-acting, offers a rapid recovery period, and rarely induces drug after effects. Dosage for Propofol, as for all licensed drugs, is governed by the FDA. Propofol is primarily metabolized via the liver, at one time it was contraindicated for cats with hepatic liver (HL), however studies undertaken at Winn Feline Health concluded Propofol can be used for cats with HL.
Ketamine, (DA) a somewhat controversial
drug, has been widely used as both a pre-anesthetic drug, and in combination
with other drugs, such as Acepromazine, for full anesthesia for some
procedures. It is generally considered safe, although some people believe that
certain breeds of cats or dogs may be at risk with its use. Ketamine is
non-narcotic and non-barbiturate, but interestingly, is a hallucinogenic and is
used by some people as a
recreational drug for that purpose. Ketamine shouldn't't be used in
animals with hypertension, heart disease, liver disease, kidney disease, head
trauma or known seizures. Ketamine may interact with other medications. Consult
with your veterinarian to determine if other drugs your pet is receiving
might
interact with ketamine; for example, narcotics, and diazepam, halothane,
chloramphenicol and thyroid medication.
Inhalant Anesthetics
Isofluorane
revolutionized veterinary
anesthesia
because of its safety (particularly with older or compromised
patients), rapid recovery of the patient after surgery, and the fact that it
will not likely to induce nor exacerbate heart arrhythmias. Isofluorane recently
lost its patent, so is becoming less expensive than newer inhalants, and is
still considered the anesthetic of choice in veterinary medicine for pregnant
animals (including for
C-sections) and for animals with heart problems. Sevoflurane
is relatively new, costing about four times more than Isofluorane. Halothane
costs even less than Isofluorane, and is still in popular use. Both Isofluorane
and halothane require the use of a precision vaporizer for measuring the
appropriate deliverance of anesthetic. Your veterinarian can (and should)
provide information to you as to which anesthetics they use and why.
It has been said that there is no such
thing as the perfect anesthetic, and there is always potential for risk with
any of them. As pet owners, we therefore need to do our homework prior to
allowing any procedure requiring anesthesia, and to insist on a pre-anesthetic
blood screening. This precaution is not a guarantee by any means (for instance,
Cardiomyopathy will not show up on a blood panel), but it can help your
veterinarian determine what is the best anesthetic or combination of
anesthetics for your cat. Certain conditions may not obviate the need for
anesthesia, but other precautions such as heart monitoring and/or oxygen
assistance should be added for additional safety and it is highly recommended to
confirm with your vet that they will be used during
surgical procedures.
Anesthetics –
Potential Side-effects, What You Should Know
Barbiturates (pentobarbital,
thiopental, thiamylal, methohexital)
Potential for respiratory depression with
excessive doses, contraindicated in pregnant cats. Prolonged anesthetic
recovery can also be a problem when barbiturates are used in older animals,
obese animals (which require higher dosage), or other animals with compromised
hepatic and renal function which decreases metabolism of the drugs.
Ketamine
Potential for depressed cardiac function; compromise respiratory function,
including apnea (failure to breathe and/or sudden pulmonary edema (fluid in the
lungs) for cats with cardiac disease or severe debilitation. Contraindicated for
cases of head trauma, or cats with kidney failure.
Propofol
(sold as PropoFlo, Rapinovet, and
Dipravan) Can cause apnea when inducted quickly, and over-dosage can cause
cardiac arrest, however ordinarily there are minimal effects on the
cardiovascular system.
Acepromazine
Because it is not an analgesic, Acepromazine is usually used in conjunction with
another sedative. It is contraindicated in animals with CNS (central nervous
system) lesions, and can sometimes cause hypothermia.
Halothane (inhalant)
Cardiopulmonary depression, and a risk of malignant hyperthermia in some
breeds/strains.
Isoflurane (inhalant)
Respiratory depression and cardiovascular depression.
Telazol
(tiletamine HCl and
zolazepam HCl- injectable)
A non-narcotic, non-barbiturate,
injectable anesthetic agent for dogs and cats. The use of Telazol is
contraindicated in dogs and cats with pancreatic disease. Telazol is also not
recommended for use in cats suffering from renal insufficiency.
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